Stage-specific IFN-induced and IFN gene expression reveal convergence of type I and type II IFN and highlight their role in both acute and chronic stage of pathogenic SIV infection

Interferons (IFNs) play a major role in controlling viral infections including HIV/SIV infections. Persistent up-regulation of interferon stimulated genes (ISGs) is associated with chronic immune activation and progression in SIV/HIV infections, but the respective contribution of different IFNs is u...

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Udgivet i:PLoS One
Main Authors: Echebli, Nadia, Tchitchek, Nicolas, Dupuy, Stéphanie, Bruel, Timothée, Peireira Bittencourt Passaes, Caroline, Bosquet, Nathalie, Le Grand, Roger, Bourgeois, Christine, Favier, Benoit, Cheynier, Rémi, Lambotte, Olivier, Vaslin, Bruno
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764266/
https://ncbi.nlm.nih.gov/pubmed/29324751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190334
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