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TIM-3 regulates CD103(+) dendritic cell function and response to chemotherapy in breast cancer
Intratumoral CD103(+) dendritic cells (DCs) are necessary for anti-tumor immunity. Here we evaluated expression of immune regulators by CD103(+) DCs in a murine model of breast cancer and identify expression of TIM-3 as a target for therapy. Anti-TIM-3 antibody improved response to paclitaxel chemot...
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| 出版年: | Cancer Cell |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5764109/ https://ncbi.nlm.nih.gov/pubmed/29316433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.11.019 |
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