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Graph‐based optimization of epitope coverage for vaccine antigen design

Epigraph is a recently developed algorithm that enables the computationally efficient design of single or multi‐antigen vaccines to maximize the potential epitope coverage for a diverse pathogen population. Potential epitopes are defined as short contiguous stretches of proteins, comparable in lengt...

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Publicat a:Stat Med
Autors principals: Theiler, James, Korber, Bette
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763320/
https://ncbi.nlm.nih.gov/pubmed/28132437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7203
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