Combination Immunotherapy of MUC1 mRNA Nano-vaccine and CTLA-4 Blockade Effectively Inhibits Growth of Triple Negative Breast Cancer

Triple negative breast cancer (TNBC), which constitutes 10%–20% of all breast cancers, is associated with aggressive progression, a high rate of metastasis, and poor prognosis. The treatment of patients with TNBC remains a great clinical challenge. Preclinical reports support the combination immunot...

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Detaylı Bibliyografya
Yayımlandı:Mol Ther
Asıl Yazarlar: Liu, Lina, Wang, Yuhua, Miao, Lei, Liu, Qi, Musetti, Sara, Li, Jun, Huang, Leaf
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Gene & Cell Therapy 2018
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763160/
https://ncbi.nlm.nih.gov/pubmed/29258739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.10.020
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