Functional Isolation of Tumor-Initiating Cells using Microfluidic-Based Migration Identifies Phosphatidylserine Decarboxylase as a Key Regulator

Isolation of tumor-initiating cells currently relies on markers that do not reflect essential biologic functions of these cells. We proposed to overcome this limitation by isolating tumor-initiating cells based on enhanced migration, a function tightly linked to tumor-initiating potential through ep...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Yu-Chih, Humphries, Brock, Brien, Riley, Gibbons, Anne E., Chen, Yu-Ting, Qyli, Tonela, Haley, Henry R., Pirone, Matthew E., Chiang, Benjamin, Xiao, Annie, Cheng, Yu-Heng, Luan, Yi, Zhang, Zhixiong, Cong, Jason, Luker, Kathryn E., Luker, Gary D., Yoon, Euisik
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762897/
https://ncbi.nlm.nih.gov/pubmed/29321615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18610-5
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