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Validation of a liquid chromatographic method for the pharmaceutical quality control of products containing elacridar()

Many anticancer drugs have an impaired bioavailability and poor brain penetration because they are substrates to drug efflux pumps such as P-glycoprotein and Breast Cancer Resistance Protein. Elacridar is a strong inhibitor of these two drug efflux pumps and therefore has great potential to improve...

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Detalhes bibliográficos
Publicado no:J Pharm Anal
Main Authors: Sawicki, Emilia, Hillebrand, Michel J., Rosing, Hilde, Schellens, Jan H.M., Nuijen, Bastiaan, Beijnen, Jos H.
Formato: Artigo
Idioma:Inglês
Publicado em: Xi'an Jiaotong University 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762608/
https://ncbi.nlm.nih.gov/pubmed/29403992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2016.04.005
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