Validation of a liquid chromatographic method for the pharmaceutical quality control of products containing elacridar()

Many anticancer drugs have an impaired bioavailability and poor brain penetration because they are substrates to drug efflux pumps such as P-glycoprotein and Breast Cancer Resistance Protein. Elacridar is a strong inhibitor of these two drug efflux pumps and therefore has great potential to improve...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Pharm Anal
Egile Nagusiak: Sawicki, Emilia, Hillebrand, Michel J., Rosing, Hilde, Schellens, Jan H.M., Nuijen, Bastiaan, Beijnen, Jos H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Xi'an Jiaotong University 2016
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762608/
https://ncbi.nlm.nih.gov/pubmed/29403992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2016.04.005
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