Validation of a liquid chromatographic method for the pharmaceutical quality control of products containing elacridar()

Many anticancer drugs have an impaired bioavailability and poor brain penetration because they are substrates to drug efflux pumps such as P-glycoprotein and Breast Cancer Resistance Protein. Elacridar is a strong inhibitor of these two drug efflux pumps and therefore has great potential to improve...

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Bibliografiske detaljer
Udgivet i:J Pharm Anal
Main Authors: Sawicki, Emilia, Hillebrand, Michel J., Rosing, Hilde, Schellens, Jan H.M., Nuijen, Bastiaan, Beijnen, Jos H.
Format: Artigo
Sprog:Inglês
Udgivet: Xi'an Jiaotong University 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762608/
https://ncbi.nlm.nih.gov/pubmed/29403992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2016.04.005
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