FRK inhibits breast cancer cell migration and invasion by suppressing epithelial-mesenchymal transition

The human fyn-related kinase (FRK) is a non-receptor tyrosine kinase known to have tumor suppressor activity in breast cancer cells. However, its mechanism of action has not been fully characterized. We generated FRK-stable MDA-MB-231 breast cancer cell lines and analyzed the effect on cell prolifer...

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Udgivet i:Oncotarget
Main Authors: Ogunbolude, Yetunde, Dai, Chenlu, Bagu, Edward T, Goel, Raghuveera Kumar, Miah, Sayem, MacAusland-Berg, Joshua, Ng, Chi Ying, Chibbar, Rajni, Napper, Scott, Raptis, Leda, Vizeacoumar, Frederick, Vizeacoumar, Franco, Bonham, Keith, Lukong, Kiven Erique
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762571/
https://ncbi.nlm.nih.gov/pubmed/29348886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22958
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