BRK Targets Dok1 for Ubiquitin-Mediated Proteasomal Degradation to Promote Cell Proliferation and Migration

Breast tumor kinase (BRK), also known as protein tyrosine kinase 6 (PTK6), is a non-receptor tyrosine kinase overexpressed in more that 60% of human breast carcinomas. The overexpression of BRK has been shown to sensitize mammary epithelial cells to mitogenic signaling and to promote cell proliferat...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Miah, Sayem, Goel, Raghuveera Kumar, Dai, Chenlu, Kalra, Natasha, Beaton-Brown, Erika, Bagu, Edward T., Bonham, Keith, Lukong, Kiven E.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3921129/
https://ncbi.nlm.nih.gov/pubmed/24523872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087684
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы