Radiosensitization of the PI3K inhibitor HS-173 through reduction of DNA damage repair in pancreatic cancer

Activation of PI3K/AKT pathway occurs frequently in tumors and is correlated with radioresistance. The PI3K/AKT pathway can be an important target for improvement of radiotherapy. Although adding of chemotherapy to radiation therapy regimen enhances survival in patients with locally advanced pancrea...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Park, Jung Hee, Jung, Kyung Hee, Kim, Soo Jung, Fang, Zhenghuan, Yan, Hong Hua, Son, Mi Kwon, Kim, Juyoung, Kang, Yeo Wool, Lee, Ji Eun, Han, Boreum, Lim, Joo Han, Hong, Soon-Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762560/
https://ncbi.nlm.nih.gov/pubmed/29348875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22850
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