Acid ceramidase and its inhibitors: a de novo drug target and a new class of drugs for killing glioblastoma cancer stem cells with high efficiency

Glioblastoma remains the most common, malignant primary cancer of the central nervous system with a low life expectancy and an overall survival of less than 1.5 years. The treatment options are limited and there is no cure. Moreover, almost all patients develop recurrent tumors, which typically are...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Doan, Ninh B., Alhajala, Hisham, Al-Gizawiy, Mona M., Mueller, Wade M., Rand, Scott D., Connelly, Jennifer M., Cochran, Elizabeth J., Chitambar, Christopher R., Clark, Paul, Kuo, John, Schmainda, Kathleen M., Mirza, Shama P.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762539/
https://ncbi.nlm.nih.gov/pubmed/29348854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22637
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