Glycan microarray reveal induced IgGs repertoire shift against a dietary carbohydrate in response to rabbit anti-human thymocyte therapy

Humans have circulating antibodies against diverse glycans containing N-glycolylneuraminic acid (Neu5Gc) due to function-loss mutation of the CMAH gene. This xenogenic non-human carbohydrate is abundant in red meat, xenografts and biotherapeutics. Low levels of diet-derived Neu5Gc is also present on...

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Publicado en:Oncotarget
Main Authors: Amon, Ron, Ben-Arye, Shani Leviatan, Engler, Limor, Yu, Hai, Lim, Noha, Berre, Ludmilla Le, Harris, Kristina M., Ehlers, Mario R., Gitelman, Stephen E., Chen, Xi, Soulillou, Jean-Paul, Padler-Karavani, Vered
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Research Paper: Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762506/
https://ncbi.nlm.nih.gov/pubmed/29348821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23096
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