Characterizing cis-regulatory variation in the transcriptome of histologically normal and tumor-derived pancreatic tissues

OBJECTIVE: To elucidate the genetic architecture of gene expression in pancreatic tissues. DESIGN: We performed expression quantitative trait locus (eQTL) analysis in histologically normal pancreatic tissue samples (n=95) using RNA-sequencing and the corresponding 1000 Genomes imputed germline genot...

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Publicado no:Gut
Main Authors: Zhang, Mingfeng, Lykke-Andersen, Soren, Zhu, Bin, Xiao, Wenming, Hoskins, Jason W., Zhang, Xijun, Rost, Lauren M., Collins, Irene, van de Bunt, Martijn, Jia, Jinping, Parikh, Hemang, Zhang, Tongwu, Song, Lei, Jermusyk, Ashley, Chung, Charles C., Zhou, Weiyin, Matters, Gail L., Kurtz, Robert C., Yeager, Meredith, Jensen, Torben Heick, Brown, Kevin M., Ongen, Halit, Bamlet, William R., Murray, Bradley A., McCarthy, Mark I., Chanock, Stephen J., Chatterjee, Nilanjan, Wolpin, Brian M., Smith, Jill P., Olson, Sara H., Petersen, Gloria M., Shi, Jianxin, Amundadottir, Laufey T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762429/
https://ncbi.nlm.nih.gov/pubmed/28634199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-313146
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