Characterizing cis-regulatory variation in the transcriptome of histologically normal and tumor-derived pancreatic tissues

OBJECTIVE: To elucidate the genetic architecture of gene expression in pancreatic tissues. DESIGN: We performed expression quantitative trait locus (eQTL) analysis in histologically normal pancreatic tissue samples (n=95) using RNA-sequencing and the corresponding 1000 Genomes imputed germline genot...

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מידע ביבליוגרפי
הוצא לאור ב:Gut
Main Authors: Zhang, Mingfeng, Lykke-Andersen, Soren, Zhu, Bin, Xiao, Wenming, Hoskins, Jason W., Zhang, Xijun, Rost, Lauren M., Collins, Irene, van de Bunt, Martijn, Jia, Jinping, Parikh, Hemang, Zhang, Tongwu, Song, Lei, Jermusyk, Ashley, Chung, Charles C., Zhou, Weiyin, Matters, Gail L., Kurtz, Robert C., Yeager, Meredith, Jensen, Torben Heick, Brown, Kevin M., Ongen, Halit, Bamlet, William R., Murray, Bradley A., McCarthy, Mark I., Chanock, Stephen J., Chatterjee, Nilanjan, Wolpin, Brian M., Smith, Jill P., Olson, Sara H., Petersen, Gloria M., Shi, Jianxin, Amundadottir, Laufey T.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2017
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762429/
https://ncbi.nlm.nih.gov/pubmed/28634199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-313146
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