A Phase II/III Trial of Lopinavir/Ritonavir Dosed According to the Who Pediatric Weight Band Dosing Guidelines

BACKGROUND: The World Health Organization (WHO) recommends weight band dosing of antiretrovirals for children. Data are limited describing drug exposure/safety of lopinavir/ritonavir (LPV/r) using WHO weight-band dosing. METHODS: IMPAACT P1083 was a phase II/III trial assessing the pharmacokinetics...

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Bibliographic Details
Published in:Pediatr Infect Dis J
Main Authors: Pinto, Jorge A., Capparelli, Edmund V., Warshaw, Meredith, Zimmer, Bonnie, Cressey, Tim R., Spector, Stephen A., Qin, Min, Smith, Betsy, Siberry, George K., Mirochnick, Mark
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762400/
https://ncbi.nlm.nih.gov/pubmed/29088027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/INF.0000000000001817
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