Febuxostat attenuates ER stress mediated kidney injury in a rat model of hyperuricemic nephropathy

Hyperuricemia contributes to kidney tubular injury and kidney fibrosis. However, the underlying mechanism remains unclear. Here we examined the role of RTN1A, a novel endoplasmic reticulum (ER)-associated protein and ER stress in hyperuricemic nephropathy. We first found the expression of RTN1A and...

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Vydáno v:Oncotarget
Hlavní autoři: He, Li, Fan, Ying, Xiao, Wenzhen, Chen, Teng, Wen, Jiejun, Dong, Yang, Wang, Yiyun, Li, Shiqi, Xue, Rui, Zheng, Liyang, He, John Cijiang, Wang, Niansong
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762322/
https://ncbi.nlm.nih.gov/pubmed/29340054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22784
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