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Pharmacologic Targeting of BET Proteins Attenuates Hyperuricemic Nephropathy in Rats
Hyperuricemia is an independent risk factor for renal damage and promotes the progression of chronic kidney disease. In this study, we investigated the effect of I-BET151, a small-molecule inhibitor targeting the bromodomain and extraterminal (BET) proteins, on the development of hyperuricemic nephr...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7921804/ https://ncbi.nlm.nih.gov/pubmed/33664670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.636154 |
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