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Integrative molecular network analysis identifies emergent enzalutamide resistance mechanisms in prostate cancer

Recent work demonstrates that castration-resistant prostate cancer (CRPC) tumors harbor countless genomic aberrations that control many hallmarks of cancer. While some specific mutations in CRPC may be actionable, many others are not. We hypothesized that genomic aberrations in cancer may operate in...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: King, Carly J., Woodward, Josha, Schwartzman, Jacob, Coleman, Daniel J., Lisac, Robert, Wang, Nicholas J., Van Hook, Kathryn, Gao, Lina, Urrutia, Joshua, Dane, Mark A., Heiser, Laura M., Alumkal, Joshi J.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762307/
https://ncbi.nlm.nih.gov/pubmed/29340039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22560
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