Synthetically Lethal Nanoparticles for Treatment of Endometrial Cancer

Uterine serous carcinoma, one of the most aggressive types of endometrial cancer, is characterized by poor outcomes and mutations in the tumor suppressor p53. Our objective was to engender synthetic lethality to paclitaxel, the frontline treatment for endometrial cancer, in tumors with mutant p53 an...

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Publicat a:Nat Nanotechnol
Autors principals: Ebeid, Kareem, Meng, Xiangbing, Thiel, Kristina W, Do, Anh-Vu, Geary, Sean M, Morris, Angie S, Pham, Erica L, Wongrakpanich, Amaraporn, Chhonker, Yashpal S, Murry, Daryl J, Leslie, Kimberly K, Salem, Aliasger K
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762267/
https://ncbi.nlm.nih.gov/pubmed/29203914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41565-017-0009-7
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