Multiple responses optimization in the development of a headspace gas chromatography method for the determination of residual solvents in pharmaceuticals()

An efficient generic static headspace gas chromatography (HSGC) method was developed, optimized and validated for the routine determination of several residual solvents (RS) in drug substance, using a strategy with two sets of calibration. Dimethylsulfoxide (DMSO) was selected as the sample diluent...

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Detalhes bibliográficos
Publicado no:J Pharm Anal
Main Authors: Teglia, Carla M., Montemurro, Milagros, De Zan, María M., Cámara, María S.
Formato: Artigo
Idioma:Inglês
Publicado em: Xi'an Jiaotong University 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762238/
https://ncbi.nlm.nih.gov/pubmed/29403943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2015.02.004
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