Does lung cancer mutation status and targeted therapy predict for outcomes and local control in the setting of brain metastases treated with radiation?

BACKGROUND: We investigated effects of genetic alterations in epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK), and Kirsten rat sarcoma viral oncogene homolog (KRAS) on overall survival (OS) and local control after stereotactic radiosurgery for brain metastases in non–small...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Wang, Tony J. C., Saad, Shumaila, Qureshi, Yasir H., Jani, Ashish, Nanda, Tavish, Yaeh, Andrew M., Rozenblat, Tzlil, Sisti, Michael B., Bruce, Jeffrey N., McKhann, Guy M., Lesser, Jeraldine, Halmos, Balazs, Stoopler, Mark B., Lassman, Andrew B., Cheng, Simon K., Isaacson, Steven R.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Clinical Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762012/
https://ncbi.nlm.nih.gov/pubmed/25910841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov043
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