Does lung cancer mutation status and targeted therapy predict for outcomes and local control in the setting of brain metastases treated with radiation?

BACKGROUND: We investigated effects of genetic alterations in epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK), and Kirsten rat sarcoma viral oncogene homolog (KRAS) on overall survival (OS) and local control after stereotactic radiosurgery for brain metastases in non–small...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Wang, Tony J. C., Saad, Shumaila, Qureshi, Yasir H., Jani, Ashish, Nanda, Tavish, Yaeh, Andrew M., Rozenblat, Tzlil, Sisti, Michael B., Bruce, Jeffrey N., McKhann, Guy M., Lesser, Jeraldine, Halmos, Balazs, Stoopler, Mark B., Lassman, Andrew B., Cheng, Simon K., Isaacson, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762012/
https://ncbi.nlm.nih.gov/pubmed/25910841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov043
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