Загрузка...
Upregulation of IRS1 Enhances IGF1 Response in Y537S and D538G ESR1 Mutant Breast Cancer Cells
Increased evidence suggests that somatic mutations in the ligand-binding domain of estrogen receptor [ER (ERα/ESR1)] are critical mediators of endocrine-resistant breast cancer progression. Insulinlike growth factor-1 (IGF1) is an essential regulator of breast development and tumorigenesis and also...
Сохранить в:
| Опубликовано в: : | Endocrinology |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Endocrine Society
2017
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5761602/ https://ncbi.nlm.nih.gov/pubmed/29029116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00693 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|