Prostaglandin-Endoperoxide Synthase 1 Mediates the Timing of Parturition in Mice Despite Unhindered Uterine Contractility

Cyclooxygenase (COX)-derived prostaglandins stimulate uterine contractions and prepare the cervix for parturition. Prior reports suggest Cox-1 knockout (KO) mice exhibit delayed parturition due to impaired luteolysis, yet the mechanism for late-onset delivery remains unclear. Here, we examined key f...

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Publicat a:Endocrinology
Autors principals: Herington, Jennifer L., O’Brien, Christine, Robuck, Michael F., Lei, Wei, Brown, Naoko, Slaughter, James C., Paria, Bibhash C., Mahadevan-Jansen, Anita, Reese, Jeff
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2017
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761592/
https://ncbi.nlm.nih.gov/pubmed/29029054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00647
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