Prostaglandin-Endoperoxide Synthase 1 Mediates the Timing of Parturition in Mice Despite Unhindered Uterine Contractility

Cyclooxygenase (COX)-derived prostaglandins stimulate uterine contractions and prepare the cervix for parturition. Prior reports suggest Cox-1 knockout (KO) mice exhibit delayed parturition due to impaired luteolysis, yet the mechanism for late-onset delivery remains unclear. Here, we examined key f...

Full description

Saved in:
Bibliographic Details
Published in:Endocrinology
Main Authors: Herington, Jennifer L., O’Brien, Christine, Robuck, Michael F., Lei, Wei, Brown, Naoko, Slaughter, James C., Paria, Bibhash C., Mahadevan-Jansen, Anita, Reese, Jeff
Format: Artigo
Language:Inglês
Published: Endocrine Society 2017
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761592/
https://ncbi.nlm.nih.gov/pubmed/29029054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00647
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items