High-Throughput Screening of Myometrial Calcium-Mobilization to Identify Modulators of Uterine Contractility

The uterine myometrium (UT-myo) is a therapeutic target for preterm labor, labor induction, and postpartum hemorrhage. Stimulation of intracellular Ca(2+)-release in UT-myo cells by oxytocin is a final pathway controlling myometrial contractions. The goal of this study was to develop a dual-addition...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Herington, Jennifer L., Swale, Daniel R., Brown, Naoko, Shelton, Elaine L., Choi, Hyehun, Williams, Charles H., Hong, Charles C., Paria, Bibhash C., Denton, Jerod S., Reese, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4658040/
https://ncbi.nlm.nih.gov/pubmed/26600013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143243
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