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LC, MS(n) and LC–MS/MS studies for the characterization of degradation products of amlodipine

In the present study, comprehensive stress testing of amlodipine (AM) was carried out according to International Conference on Harmonization (ICH) Q1A(R2) guideline. AM was subjected to acidic, neutral and alkaline hydrolysis, oxidation, photolysis and thermal stress conditions. The drug showed inst...

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Опубликовано в: :J Pharm Anal
Главные авторы: Tiwari, Ravi N., Shah, Nishit, Bhalani, Vikas, Mahajan, Anand
Формат: Artigo
Язык:Inglês
Опубликовано: Xi'an Jiaotong University 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761482/
https://ncbi.nlm.nih.gov/pubmed/29403913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2014.07.005
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