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Simultaneous quantification of prodrug oseltamivir and its metabolite oseltamivir carboxylate in human plasma by LC–MS/MS to support a bioequivalence study

A simple, precise and rapid liquid chromatography–tandem mass spectrometry (LC–MS/MS) method has been developed and validated for the simultaneous determination of oseltamivir and oseltamivir carboxylate, a neuraminidase inhibitor, using their deuterated analogs as internal standards (ISs). The meth...

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Bibliografische gegevens
Gepubliceerd in:J Pharm Anal
Hoofdauteurs: Gupta, Ajay, Guttikar, Swati, Shrivastav, Pranav S., Sanyal, Mallika
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Xi'an Jiaotong University 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760963/
https://ncbi.nlm.nih.gov/pubmed/29403810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2012.11.004
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