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Quantification of sibutramine and its two metabolites in human plasma by LC–ESI-MS/MS and its application in a bioequivalence study

Obesity can be considered as a chronic illness of epidemic proportion and its incidents have increased exponentially in recent years. The use of anti-obesity drugs such as sibutramine is somewhat helpful. There is a need to quantify such drugs in biological samples, which is generally quite difficul...

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Detalhes bibliográficos
Publicado no:J Pharm Anal
Main Authors: Ponnuru, Venkata Suresh, Challa, B.R., Nadendla, RamaRao
Formato: Artigo
Idioma:Inglês
Publicado em: Xi'an Jiaotong University 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760908/
https://ncbi.nlm.nih.gov/pubmed/29403750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2012.02.010
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