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RFX1 and RFX3 Transcription Factors Interact with the D Sequence of Adeno-Associated Virus Inverted Terminal Repeat and Regulate AAV Transduction

Adeno-associated virus (AAV) transduction efficiency depends on the way in which cellular proteins process viral genomes in the nucleus. In this study, we have investigated the binding of nuclear proteins to the double stranded D (dsD) sequence of the AAV inverted terminal repeat (ITRs) by electromo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Julien, Laura, Chassagne, Julie, Peccate, Cécile, Lorain, Stéphanie, Piétri-Rouxel, France, Danos, Olivier, Benkhelifa-Ziyyat, Sofia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760533/
https://ncbi.nlm.nih.gov/pubmed/29317724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18604-3
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