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SUR1-TRPM4 and AQP4 form a heteromultimeric complex that amplifies ion/water osmotic coupling and drives astrocyte swelling
Astrocyte swelling occurs after CNS injury and contributes to brain swelling, which can increase mortality. Mechanisms proffered to explain astrocyte swelling emphasize the importance of either aquaporin-4 (AQP4), an astrocyte water channel, or of Na(+)-permeable channels, which mediate cellular osm...
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| Udgivet i: | Glia |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5759053/ https://ncbi.nlm.nih.gov/pubmed/28906027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23231 |
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