Heterogeneity of aquaporin-4 localization and expression after focal cerebral ischemia underlies differences in white versus grey matter swelling

INTRODUCTION: Ischemic stroke, a major cause of mortality, is frequently accompanied by life-threatening cerebral edema. Aquaporin-4 (Aqp4), an astrocytic transmembrane water channel, is an important molecular contributor to cerebral edema formation. Past studies of Aqp4 expression and localization...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Stokum, Jesse A., Mehta, Rupal I., Ivanova, Svetlana, Yu, Edward, Gerzanich, Volodymyr, Simard, J. Marc
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588314/
https://ncbi.nlm.nih.gov/pubmed/26419740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0239-6
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