Conventional and pioneer modes of glucocorticoid receptor interaction with enhancer chromatin in vivo

Glucocorticoid hormone plays a major role in metabolism and disease. The hormone-bound glucocorticoid receptor (GR) binds to a specific set of enhancers in different cell types, resulting in unique patterns of gene expression. We have addressed the role of chromatin structure in GR binding by mappin...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Johnson, Thomas A, Chereji, Răzvan V, Stavreva, Diana A, Morris, Stephanie A, Hager, Gordon L, Clark, David J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Gene regulation, Chromatin and Epigenetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758879/
https://ncbi.nlm.nih.gov/pubmed/29126175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1044
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