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The Opioid-Sparing Effect of Perioperative Dexmedetomidine Combined with Oxycodone Infusion during Open Hepatectomy: A Randomized Controlled Trial

Background: A large right subcostal incision performed by open hepatectomy is associated with significant post-operative pain and distress. However, post-operative analgesia solutions still need to be devised. We investigated the effects of intra- and post-operative infusion of dexmedetomidine (Dex)...

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Publicat a:Front Pharmacol
Autors principals: Zhang, Benhou, Wang, Guifang, Liu, Xiaopeng, Wang, Tian-Long, Chi, Ping
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758592/
https://ncbi.nlm.nih.gov/pubmed/29354054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00940
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