Mechanistic insights into the role of prenyl-binding protein PrBP/δ in membrane dissociation of phosphodiesterase 6

Isoprenylated proteins are associated with membranes and their inter-compartmental distribution is regulated by solubilization factors, which incorporate lipid moieties in hydrophobic cavities and thereby facilitate free diffusion during trafficking. Here we report the crystal structure of a solubil...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Qureshi, Bilal M., Schmidt, Andrea, Behrmann, Elmar, Bürger, Jörg, Mielke, Thorsten, Spahn, Christian M. T., Heck, Martin, Scheerer, Patrick
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758567/
https://ncbi.nlm.nih.gov/pubmed/29311697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02569-y
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