Mechanistic insights into the role of prenyl-binding protein PrBP/δ in membrane dissociation of phosphodiesterase 6

Isoprenylated proteins are associated with membranes and their inter-compartmental distribution is regulated by solubilization factors, which incorporate lipid moieties in hydrophobic cavities and thereby facilitate free diffusion during trafficking. Here we report the crystal structure of a solubil...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Qureshi, Bilal M., Schmidt, Andrea, Behrmann, Elmar, Bürger, Jörg, Mielke, Thorsten, Spahn, Christian M. T., Heck, Martin, Scheerer, Patrick
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758567/
https://ncbi.nlm.nih.gov/pubmed/29311697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02569-y
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