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Mechanistic insights into the role of prenyl-binding protein PrBP/δ in membrane dissociation of phosphodiesterase 6

Isoprenylated proteins are associated with membranes and their inter-compartmental distribution is regulated by solubilization factors, which incorporate lipid moieties in hydrophobic cavities and thereby facilitate free diffusion during trafficking. Here we report the crystal structure of a solubil...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Qureshi, Bilal M., Schmidt, Andrea, Behrmann, Elmar, Bürger, Jörg, Mielke, Thorsten, Spahn, Christian M. T., Heck, Martin, Scheerer, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5758567/
https://ncbi.nlm.nih.gov/pubmed/29311697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02569-y
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