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Structure of p300 in complex with acyl-CoA variants

Histone acetylation plays an important role in transcriptional activation. Histones are also modified by chemically diverse acylations that are frequently deposited by p300, a transcriptional coactivator that uses a number of different acyl-CoA cofactors. Here we report that while p300 is a robust a...

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Bibliografische gegevens
Gepubliceerd in:Nat Chem Biol
Hoofdauteurs: Kaczmarska, Zuzanna, Ortega, Esther, Goudarzi, Afsaneh, Huang, He, Kim, Sunjoo, Márquez, José A, Zhao, Yingming, Khochbin, Saadi, Panne, Daniel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757799/
https://ncbi.nlm.nih.gov/pubmed/27820805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2217
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