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Role of cationic drug-sensitive transport systems at the blood-cerebrospinal fluid barrier in para-tyramine elimination from rat brain

BACKGROUND: para-Tyramine (p-TA) is a biogenic amine which is involved in multiple neuronal signal transductions. Since the concentration of p-TA in dog cerebrospinal fluid (CSF) has been reported to be greater than that in plasma, it is proposed that clearance of cerebral p-TA is important for norm...

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Bibliographic Details
Published in:Fluids Barriers CNS
Main Authors: Akanuma, Shin-ichi, Yamazaki, Yuhei, Kubo, Yoshiyuki, Hosoya, Ken-ichi
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757291/
https://ncbi.nlm.nih.gov/pubmed/29307307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-017-0087-9
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