Regulatory T cells are expanded by Teriparatide treatment in humans and mediate intermittent PTH‐induced bone anabolism in mice

Teriparatide is a bone anabolic treatment for osteoporosis, modeled in animals by intermittent PTH (iPTH) administration, but the cellular and molecular mechanisms of action of iPTH are largely unknown. Here, we show that Teriparatide and iPTH cause a ~two‐threefold increase in the number of regulat...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Yu, Mingcan, D'Amelio, Patrizia, Tyagi, Abdul Malik, Vaccaro, Chiara, Li, Jau‐Yi, Hsu, Emory, Buondonno, Ilaria, Sassi, Francesca, Adams, Jonathan, Weitzmann, M Neale, DiPaolo, Richard, Pacifici, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757282/
https://ncbi.nlm.nih.gov/pubmed/29158349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744421
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