Human cytomegalovirus miR-UL112-1 promotes the down-regulation of viral immediate early-gene expression during latency to prevent T-cell recognition of latently infected cells

Human cytomegalovirus, a member of the herpesvirus family, can cause significant morbidity and mortality in immune compromised patients resulting from either primary lytic infection or reactivation from latency. Latent infection is associated with a restricted viral transcription programme compared...

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Gepubliceerd in:J Gen Virol
Hoofdauteurs: Lau, Betty, Poole, Emma, Van Damme, Ellen, Bunkens, Lieve, Sowash, Madeleine, King, Harry, Murphy, Eain, Wills, Mark, Van Loock, Marnix, Sinclair, John
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Microbiology Society 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756489/
https://ncbi.nlm.nih.gov/pubmed/27411311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000546
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