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MCPIP1/regnase-I inhibits simian immunodeficiency virus and is not counteracted by Vpx
We have previously shown that the cellular RNase MCPIP1/regnase-1 potently blocks HIV-1 infection in resting CD4(+) T-cells. As simian immunodeficiency virus (SIV) encodes an accessory protein named Vpx, which enhances viral replication in resting CD4(+) T-cells by degrading the cellular restriction...
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| Publicado no: | J Gen Virol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Microbiology Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5756484/ https://ncbi.nlm.nih.gov/pubmed/27075251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000482 |
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