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Hypoxic Induction Of Vasorin Regulates Notch1 Turnover To Maintain Glioma Stem-Like Cells

Tumor hypoxia is associated with poor patient survival and is a characteristic of glioblastoma. Notch signaling is implicated in maintaining glioma stem-like cells (GSCs) within the hypoxic niche, although the molecular mechanisms linking hypoxia to Notch activation have not been clearly delineated....

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Bibliografske podrobnosti
izdano v:Cell Stem Cell
Main Authors: Man, Jianghong, Yu, Xingjiang, Huang, Haidong, Zhou, Wenchao, Xiang, Chaomei, Huang, Haohao, Miele, Lucio, Liu, Zhenggang, Bebek, Gurkan, Bao, Shideng, Yu, Jennifer S.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756127/
https://ncbi.nlm.nih.gov/pubmed/29198941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2017.10.005
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