Deep Brain Stimulation Reverses Anhedonic-Like Behavior in a Chronic Model of Depression: Role of Serotonin and Brain Derived Neurotrophic Factor

BACKGROUND: Deep brain stimulation (DBS) is being investigated as a treatment for major depression, but its mechanisms of action are still unknown. We have studied the effects of ventromedial prefrontal cortex (vmPFC) stimulation in a chronic model of depression and assessed the involvement of the s...

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Publicat a:Biol Psychiatry
Autors principals: Hamani, Clement, Machado, Danilo C., Hipólide, Débora C., Dubiela, Francisco P., Suchecki, Deborah, Macedo, Carlos E., Tescarollo, Fabio, Martins, Uilton, Covolan, Luciene, Nobrega, José N.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5756076/
https://ncbi.nlm.nih.gov/pubmed/22000731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2011.08.025
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