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Glutamate reduces glucose utilization while concomitantly enhancing AQP9 and MCT2 expression in cultured rat hippocampal neurons

The excitatory neurotransmitter glutamate has been reported to have a major impact on brain energy metabolism. Using primary cultures of rat hippocampal neurons, we observed that glutamate reduces glucose utilization in this cell type, suggesting alteration in mitochondrial oxidative metabolism. The...

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Detalhes bibliográficos
Main Authors: Tescarollo, Fabio, Covolan, Luciene, Pellerin, Luc
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130107/
https://ncbi.nlm.nih.gov/pubmed/25161606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00246
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