Exogenous BMP7 in aortae of rats with chronic uremia ameliorates expression of profibrotic genes, but does not reverse established vascular calcification

Hyperphosphatemia and vascular calcification are frequent complications of chronic renal failure and bone morphogenetic protein 7 (BMP7) has been shown to protect against development of vascular calcification in uremia. The present investigation examined the potential reversibility of established ur...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Gravesen, Eva, Lerche Mace, Maria, Nordholm, Anders, Hofman-Bang, Jacob, Hruska, Keith, Haagen Nielsen, Carsten, Kjær, Andreas, Olgaard, Klaus, Lewin, Ewa
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755916/
https://ncbi.nlm.nih.gov/pubmed/29304096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190820
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