Exogenous BMP7 in aortae of rats with chronic uremia ameliorates expression of profibrotic genes, but does not reverse established vascular calcification

Hyperphosphatemia and vascular calcification are frequent complications of chronic renal failure and bone morphogenetic protein 7 (BMP7) has been shown to protect against development of vascular calcification in uremia. The present investigation examined the potential reversibility of established ur...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gravesen, Eva, Lerche Mace, Maria, Nordholm, Anders, Hofman-Bang, Jacob, Hruska, Keith, Haagen Nielsen, Carsten, Kjær, Andreas, Olgaard, Klaus, Lewin, Ewa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755916/
https://ncbi.nlm.nih.gov/pubmed/29304096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190820
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