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Klotho and activin A in kidney injury: plasma Klotho is maintained in unilateral obstruction despite no upregulation of Klotho biosynthesis in the contralateral kidney

In a new paradigm of etiology related to chronic kidney disease-mineral and bone disorder (CKD-MBD), kidney injury may cause induction of factors in the injured kidney that are released into the circulation and thereby initiate and maintain renal fibrosis and CKD-MBD. Klotho is believed to ameliorat...

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Publicat a:Am J Physiol Renal Physiol
Autors principals: Nordholm, Anders, Mace, Maria L., Gravesen, Eva, Hofman-Bang, Jacob, Morevati, Marya, Olgaard, Klaus, Lewin, Ewa
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031917/
https://ncbi.nlm.nih.gov/pubmed/29187373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00528.2017
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