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Metformin in combination with cisplatin inhibits cell viability and induces apoptosis of human ovarian cancer cells by inactivating ERK 1/2

Metformin protects against insulin resistance by restoring insulin sensitivity and may also possess anticancer activity. The aim of the present study was to investigate the effects of metformin alone or combined with cisplatin (DDP) on the cell viability and apoptosis of HO-8910 human ovarian cancer...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Dang, Jian-Hong, Jin, Zhi-Jun, Liu, Xiao-Jun, Hu, Dian, Wang, Jing, Luo, Yan, Li, Ling-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755135/
https://ncbi.nlm.nih.gov/pubmed/29344202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7176
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