Downregulation of ATG14 by EGR1-MIR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagy

Cisplatin is commonly used in ovarian cancer treatment by inducing apoptosis in cancer cells as a result of lethal DNA damage. However, the intrinsic and acquired resistance to cisplatin in cancer cells remains a big challenge for improving overall survival. The cyto-protective functions of autophag...

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Publicat a:Autophagy
Autors principals: He, Jun, Yu, Jing-Jie, Xu, Qing, Wang, Lin, Zheng, Jenny Z, Liu, Ling-Zhi, Jiang, Bing-Hua
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Translational Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502709/
https://ncbi.nlm.nih.gov/pubmed/25650716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1009781
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