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In vivo and in vitro induction of the apoptotic effects of oxysophoridine on colorectal cancer cells via the Bcl-2/Bax/caspase-3 signaling pathway

Oxysophoridine (OSR) is a major active alkaloid extracted from Sophoraalopecuroides L. The aim of the present study was to investigate the induction of the apoptotic effects of OSR on colorectal cancer cells in vivo and in vitro. The results of the MTT and colony formation assays demonstrated that t...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Jin, Shao-Ju, Yang, Yun, Ma, Lei, Ma, Ben-Hui, Ren, Li-Ping, Guo, Liu-Cheng, Wang, Wen-Bao, Zhang, Yan-Xin, Zhao, Zhi-Jun, Cui, Mingchen
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755128/
https://ncbi.nlm.nih.gov/pubmed/29344242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7227
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