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Bax Regulates Production of Superoxide in Both Apoptotic and Nonapoptotic Neurons: Role of Caspases

A Bax- and, apparently, mitochondria-dependent increase in superoxide (O(2)(·−)) and other reactive oxygen species (ROS) occurs in apoptotic superior cervical ganglion (SCG) and cerebellar granule (CG) neurons. Here we show that Bax also lies upstream of ROS produced in nonapoptotic neurons and pres...

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書誌詳細
主要な著者: Kirkland, Rebecca A., Saavedra, Geraldine M., Cummings, Brian S., Franklin, James L.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004742/
https://ncbi.nlm.nih.gov/pubmed/21123558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2862-10.2010
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