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Phosphorylation of Ser6 in hnRNPA1 by S6K2 regulates glucose metabolism and cell growth in colorectal cancer

Abnormal glucose metabolism is critical in colorectal cancer (CRC) development. Expression of the pyruvate kinase (PK) M2 isoform, rather than the PKM1 isoform, serves important functions in reprogramming the glucose metabolism of cancer cells. Preferential expression of PKM2 is primarily driven by...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Sun, Yan, Luo, Man, Chang, Guilin, Ren, Weiying, Wu, Kefen, Li, Xi, Shen, Jiping, Zhao, Xiaoping, Hu, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755035/
https://ncbi.nlm.nih.gov/pubmed/29344170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7085
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