NLS-RARα is a novel transcriptional factor

Acute promyelocytic leukemia (APL) is characterized by the presence of the promyelocytic leukemia (PML)-retinoic acid receptor-α (RAR-α) fusion protein. PML-RARα can be cleaved by neutrophil elastase (NE) in several positions in cells in the promyelocytic stage, nuclear location signal (NLS)-negativ...

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Bibliographic Details
Published in:Oncol Lett
Main Authors: Jiang, Kai-Ling, Zhong, Liang, Yang, Xiao-Qun, Ma, Peng-Peng, Wang, Hui, Zhu, Xin-Yu, Liu, Bei-Zhong
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2017
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5754919/
https://ncbi.nlm.nih.gov/pubmed/29344139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7132
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